Quick Overview

High-purity Selank, a synthetic heptapeptide analog derived from the immunomodulatory peptide tuftsin, synthesized specifically for in vitro laboratory research and development. Formulated as a sterile, lyophilized powder to ensure maximum stability and precision in neurobiological, cognitive, and molecular research models.

Product Description

Selank is a synthetic heptapeptide comprising the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, structurally modeled after the endogenous human peptide tuftsin with an added C-terminal prolyl-glycyl-proline tail for improved enzymatic stability. In scientific literature, Selank has been extensively evaluated for its neuromodulatory properties, impact on monoamine neurotransmitter turnover, and influence on brain-derived neurotrophic factor (BDNF) expression. In vitro, it provides a reliable model for studying cellular signal transduction, anxiety-related behavioral response pathways, and neuroprotection under induced stress conditions.

Common Research Applications:

• Neuroprotection Studies: Investigating cellular survival pathways and protection against oxidative and metabolic stress models.
• BDNF & Neurotrophin Modulation: Observing transcriptional regulation of brain-derived neurotrophic factors and associated receptor cascades.
• Monoamine Regulation: Analyzing serotonin, dopamine, and norepinephrine turnover rates in experimental neural culture models.
• Enzymatic Stability: Assessing the pharmacokinetic enhancements provided by the C-terminal extension against rapid peptide degradation.

Technical Specifications

Storage and Reconstitution

To maintain peptide integrity and stability, please adhere to standard laboratory handling guidelines:

• Lyophilized Form (Dry Powder): Store desiccated at -20°C (or below) upon receipt. While stable at room temperature for brief transit periods, long-term freezing is required to prevent degradation.
• Reconstitution: Reconstitute using bacteriostatic water or sterile water for injection. Introduce the diluent carefully and gently swirl the vial until dissolved. Do not shake vigorously, as this can fracture the peptide bonds.
• Liquid Storage (Reconstituted): Once reconstituted, the solution should be stored at 2°C to 8°C (refrigerated) and utilized within 14 to 30 days. For extended experimental timelines, aliquot the solution into individual vials and freeze at -20°C to avoid repeated freeze-thaw cycles.

Regulatory & Safety Disclaimer